Factory Price API 99% Cepharanthine 481-49-2 GMP Manufacturer CAS NO.481-49-2

Cepharanthine has potential anti-tumor and coronavirus-eliminating effects. The single application of fenugreek can play an anti-tumor effect by inhibiting the proliferation of tumor cells and enhancing the body's immunity. What is more promising is that fenugreek combined with chemotherapeutic drugs can improve the efficacy of chemotherapy by reducing the drug resistance of cells. The main mechanism may be that fenugreek can increase the accumulation of anticancer drugs in cells by interfering with the function of the plasma membrane. In addition, fenugreek can also improve the sensitivity of tumor cells to radiotherapy. Direct anti-tumor effect of fenugreek: fenugreek can enhance the body's anti-tumor ability by enhancing the body's immune response. Macrophages can specifically recognize and kill tumor cells and play a crucial role in anti-tumor immunity. However, in individuals with tumorigenesis, macrophages are often inhibited. Chrysanthin can activate macrophages, which may be related to its effect on tumor therapy. In addition, the activation of chitosan by T cells or direct action on macrophages is an important mechanism of tumor inhibition. It has anti-tumor effects by enhancing the body's anti-tumor immunity by acting on macrophages, T cells, NK cells, etc. It may be a multi-target and multi-effect drug, and its anti-tumor pharmacology is complex, and its molecular mechanism needs to be further explored. Based on the experimental results in a variety of tumor cells, the anti-tumor effect of fenugreek is certain. Cyclamenin increases the sensitivity of tumor cells to chemotherapy: The resistance of tumor cells to various chemotherapeutic drugs is a major obstacle in the chemotherapy of various cancers. The phenomenon that tumor cells are resistant to a variety of cytotoxic drugs with different structures and properties is called multidrug resistance. Dermatin has the effect of eliminating MDR. A possible mechanism by which fenugreek increases the accumulation of chemotherapeutic drugs in tumor cells is that it interacts directly with P-gp or binds to phosphatidylserine in the plasma membrane to eliminate MDR. By interfering with the function of the plasma membrane, it promotes the accumulation of anticancer drugs in MDR cells, thereby improving the efficacy of anticancer drugs. It can inhibit the transport function of P-gp, so it has an inhibitory effect on the drug resistance of many MDR cells that highly express P-gp. Drug accumulation in cells and reversal of MRP7-mediated MDR.

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API(Active Pharmaceutical Ingredient)

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Based on 8 years of R&D and production experience of SZO Chem Group, Our group has established a team of advanced special organic chemical synthesis technologies. In addition to synthesizing products in existing catalogs, We also provid customized products to meet the different needs of customers.The group is equipped with an independent raw material warehouse, finished product warehouse and solvent/auxiliary material warehouse totaling 4000m1002. Configure and manage according to EUGMP requirements. Each warehouse is equipped with a waiting area, a qualified product area, and a non-conforming product warehouse. At the same time, the finished product warehouse also has a return area and a recall area. The above areas are monitored for temperature and humidity.
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